Ketamine is a drug that is mostly used as a palliative in humans and animals. In recent years, it has also been studied for its potential use in treating certain mental health conditions, such as depression and anxiety. If a patient and their doctor decide to try ketamine for the treatment of depression, The process …
The mechanism of action underlying ketamine’s antidepressant effects Ketamine affects multiple neurotransmitter systems, including the opioidergic, monoaminergic, glutamatergic, and muscarinic systems, as well as substance P and sigma receptors. Early work by Skolnick and colleagues implicated the glutamatergic system in depression [7], and research over the past three decades further implicated the NMDA receptor in …
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Psychedelic drug therapy has put ketamine in the spotlight Ketamine is an anesthetic used to sedate both humans and pets, and it’s a favorite of party goers seeking a psychedelic high. Now it’s also the subject of an enormous amount of interest as a fast-acting treatment for depression and other serious mental health conditions. Despite …
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